UPF1-like helicases play roles in telomeric heterochromatin formation and X-chromosome inactivation and we focus here on variant surface glycoprotein (VSG) exclusion-factor-2 (VEX2), a UPF1-related pr

NIAID Data Ecosystem50

2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI

蛋白质结构解析

锥虫抗原变异

2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI Descriptor: VARIANT SURFACE GLYCOPROTEIN MITAT 1.2, alpha-D-mannopyranose-(1-4)-2-

Protein Data Bank Japan2024-10-23 更新30

Loss of an ectopic VSG is dependent on active transcription and does not disrupt the number or variety of templates used to repair a BES DSB. Transcription dependent loss of an ectopic VSG

锥虫抗原变异

VSG变异表面糖蛋白

In the mammalian host, Trypanosoma brucei is coated in a single variant surface glycoprotein (VSG) species. Stochastic switching of the expressed VSG allows the parasite to escape detection by the hos

NIAID Data Ecosystem60

Up regulated Variant Surface Glycoproteins under TDP1 overexpression

锥虫免疫逃逸

VSG变异表面糖蛋白

Trypanosoma brucei parasites successfully evade the host immune system by periodically switching the dense coat of Variant Surface Glycoproteins (VSG) at the cell surface. Each parasite expresses VSGs

NIAID Data Ecosystem50

Trypanosoma brucei Lister427 strains

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