Construction of Bispirooxindole Heterocycles via Palladium-Catalyzed Ring-Opening Formal [3 + 2]-Cycloaddition of Spirovinylcyclopropyl Oxindole and 3‑Oxindole Derivatives
收藏NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Construction_of_Bispirooxindole_Heterocycles_via_Palladium-Catalyzed_Ring-Opening_Formal_3_2_-Cycloaddition_of_Spirovinylcyclopropyl_Oxindole_and_3_Oxindole_Derivatives/7645112
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资源简介:
A palladium-catalyzed ring-opening
oxo-formal [3 + 2]-cycloaddition
reaction of novel donor–acceptor spirovinylcyclopropyl oxindole
with 3-oxindole is described. The developed protocol provides facile
access to oxo-bispirooxindole derivatives in good yields (up to 82%
yield) with excellent diastereoselectivities (up to 20:1 dr).
创建时间:
2019-01-29



