Construction of Bispirooxindole Heterocycles via Palladium-Catalyzed Ring-Opening Formal [3 + 2]-Cycloaddition of Spirovinylcyclopropyl Oxindole and 3‑Oxindole Derivatives
收藏NIAID Data Ecosystem2026-03-10 收录
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资源简介：
A palladium-catalyzed ring-opening oxo-formal [3 + 2]-cycloaddition reaction of novel donor–acceptor spirovinylcyclopropyl oxindole with 3-oxindole is described. The developed protocol provides facile access to oxo-bispirooxindole derivatives in good yields (up to 82% yield) with excellent diastereoselectivities (up to 20:1 dr).
创建时间：
2019-01-29
