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A Gene Encoding a Homologue of Dolichol Phosphate-β-d-Mannose Synthase Is Required for Infection of Streptomyces coelicolor A3(2) by Phage φC31

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PubMed Central2026-05-16 收录
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We have shown previously that a gene encoding a homologue to the eukaryotic dolichol-phosphate-d-mannose, protein O-d-mannosyltransferase, was required for φC31 infection of Streptomyces coelicolor. Here we show that a gene encoding the homologue to dolichol-phosphate-mannose synthase is also essential for phage sensitivity. These data confirm the role of glycosylation in the phage receptor for φC31 in S. coelicolor.

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