p27 binds to promoters of multiple genes leading to their repression
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20068
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资源简介：
The role of the cyclin-cdk inhibitor p27 in tumorigenesis is still a controversial matter. We demonstrate here that p27 negatively regulates transcription of a number of genes (p27-target genes) involved in key cellular functions as RNA processing, translation, respiration and cell proliferation. Crosslinked chromatin from quiescent NIH3T3 cells was sonicated, incubated overnight with the rabbit anti-p27 and IgG antibodies as control
创建时间：
2012-12-06
