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Fibrosis and atrial fibrillation in Scn1b null mice

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP267554
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Scn1b-/- mice are a model of Early Infantile Developmental Epileptic Encephalopathy (EIDEE). These mice exhibit characteristic seen in patients such as spontaneous siezures, ataxia, growth abnormalites, and a high incidence of premature mortality. The goal of this study was to identify changes in gene expression between Scn1b wild-type and Scn1b-/- mice in the atria Overall design: RNA-Seq in cardiac atrial tissue from 16-day old wild type (WT) and Scn1b-/- mice
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2020-06-20
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