Caspase-10 affects PBC pathogenesis
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP388788
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资源简介：
The loss of functional caspase-10 promotes inflammatory cell death in macrophages and a fibrotic response of hepatic stellate cells, which may affect the pathogenesis of PBC. Overall design: To explore the role of caspase-10, we performed RNA-seq using samples from caspase-10 or caspase-8 KO U937 macrophages, upon immune stimulation such as that with lipopolysaccharide (LPS), TNF-a, or Z-VAD+cycloheximide+TNF-a (ZCT).
创建时间：
2023-02-06
