Crystal structure of E.Coli DsbA in complex with compound 17

Crystal structure of E.Coli DsbA in complex with compound 17 Descriptor: 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-serine, Thiol:disulfide interchange protein Authors: Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. Deposit date: 2014-09-11 Release date: 2015-01-21 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015大肠杆菌DsbA与化合物17结合的晶体结构 描述符：1,2-乙二醇（1,2-ETHANEDIOL）、N-({4-甲基-2-[4-(三氟甲基)苯基]-1,3-噻唑-5-基}羰基)-L-丝氨酸、巯基-二硫键互换蛋白（Thiol:disulfide interchange protein） 作者：Adams, L.A.、Sharma, P.、Mohanty, B.、Ilyichova, O.V.、Mulcair, M.D.、Williams, M.L.、Gleeson, E.C.、Totsika, M.、Doak, B.C.、Caria, S.、Rimmer, K.、Shouldice, S.R.、Vazirani, M.、Headey, S.J.、Plumb, B.R.、Martin, J.L.、Heras, B.、Simpson, J.S.、Scanlon, M.J. 提交日期：2014-09-11 发布日期：2015-01-21 最后修改日期：2024-10-23 实验方法：X射线衍射（X-RAY DIFFRACTION）（分辨率1.55 Å） 引用文献：《基于片段筛选的大肠杆菌DsbA抑制剂设计》（Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA），发表于Angew.Chem.Int.Ed.Engl.，2015年，第54卷