Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days

Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... Authors: Yuan, M, Wilson, I.A. Deposit date: 2023-11-17 Release date: 2024-03-13 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024

小鼠PLD3与5'磷酸化单链DNA（5'Pi-ssDNA）共结晶9天的晶体结构。配体描述：2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose）、5'-3'核酸外切酶PLD3（5'-3' exonuclease PLD3）等。作者：Yuan, M、Wilson, I.A.。沉积日期：2023-11-17。发布日期：2024-03-13。末次修改日期：2024-06-19。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.73 Å）。引用文献：《疾病相关溶酶体核酸外切酶PLD3与PLD4的结构及机制解析》（Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4），《Structure》，第32卷，2024年。