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Dragonbloodin A1 and A2: Flavan Trimers and Anti-inflammatory Principles from Sanguis Draconis

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NIAID Data Ecosystem2026-03-09 收录
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Two flavan trimers, dragonbloodin A1 (1) and A2 (2), were isolated as diastereomers from sanguis draconis, a traditional Chinese medicine for regulating blood. The structures of 1 and 2 were elucidated by spectroscopic analysis and X-ray diffraction. Possible interactions between 1 and 2 were discussed, and possible biosynthesis pathways were deduced. Compounds 1, 2, and their racemic mixture all exhibited inhibition of human neutrophil elastase in a dose-dependent manner.

创建时间:
2016-04-11
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