遇见数据集

Alzheimer Disease PGS Aggregated Ranked

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Zenodo2024-05-16 更新2026-05-26 收录
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This dataset represents a resource for Alzheimer's Disease Polygenic Scores (AD PGSs) with enhanced annotations and aggregated rankings of genetic variants. Curated and annotated PGS files are in AD_aggregated_ranks.csv AD_aggregated_ranks.csv contains aggregtaed ranks of genetic variants based on the effect weight across mulitple PGSs.Below are the descriptions of the columns in the AD_aggregated_ranks.csv: hm_rsID: Reference SNP ID from dbSNP database.hm_chr: Chromosome number where the SNP is located.hm_pos: Position of the SNP on the chromosome.annot.symbol: Gene symbol associated with the SNP.annot.type: Type of genetic annotation (e.g., intronic, exonic).weighted_means: Weighted mean of polygenic scores across different studies.mean reciprocal rank (Dowdall): Mean reciprocal rank of SNPs, used in rank aggregation, following Dowdall's method.RRA_score: Robust Rank Aggregation score.Stuart_score: Score based on Stuart's method of rank aggregation.Min_score: Minimum rank score across all aggregated studies.Geo_score: Geometric mean score.Mean_score: Arithmetic mean of all rank scores.Med_score: Median of the rank scores.

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Zenodo
创建时间:
2024-05-15
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