Crystal structure of an inverse agonist antipsychotic drug derivative-bound 5-HT2C
收藏Protein Data Bank Japan2024-10-16 更新2026-06-30 收录
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Crystal structure of an inverse agonist antipsychotic drug derivative-bound 5-HT2C Descriptor: 1-[(4-fluorophenyl)methyl]-1-[(8~{S})-5-methyl-5-azaspiro[2.5]octan-8-yl]-3-[[4-(2-methylpropoxy)phenyl]methyl]urea, 5-hydroxytryptamine receptor 2C,Soluble cytochrome b562 Authors: Oguma, T, Asada, H, Sekiguchi, Y, Imono, M, Iwata, S, Kusakabe, K. Deposit date: 2024-05-23 Release date: 2024-08-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Dual 5-HT 2A and 5-HT 2C Receptor Inverse Agonist That Affords In Vivo Antipsychotic Efficacy with Minimal hERG Inhibition for the Treatment of Dementia-Related Psychosis. J.Med.Chem., 67, 2024
创建时间：
2024-05-23
