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Clonal Selection Drives Genetic Divergence of Metastatic Medulloblastoma [Illumina Infinium HumanMethylation27 Beadchip v1.2]

ChEBI2011-12-13 更新2026-07-21 收录

母细胞瘤转移机制

肿瘤克隆演化表观遗传学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-34355 数据链接链接失效反馈

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Clonal Selection Drives Genetic Divergence of Metastatic Medulloblastoma [Illumina Infinium HumanMethylation27 Beadchip v1.2]

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创建时间：

2011-12-13

母细胞瘤转移机制

肿瘤微环境细胞分析

To comprehensively elucidate the cellular composition of neuroblastoma bone metastatic and non-metastatic microenvironment. Bone marrow tissue from neuroblastoma patients were obtained from surgical r

NIAID Data Ecosystem120

Fluid shear stress activates a targetable mechano-metastatic cascade to promote medulloblastoma metastasis

母细胞瘤转移机制

机械生物学治疗靶点

Biofluidflow generates fluid shear stress(FSS), a mechanical force widely present in tissue microenvironment. How brain tumor growth alters the conduit of biofluid, thereby impacting FSS-regulated can

NIAID Data Ecosystem60

Data_Sheet_4_Prp19 Is an Independent Prognostic Marker and Promotes Neuroblastoma Metastasis by Regulating the Hippo-YAP Signaling Pathway.ZIP

母细胞瘤预后标志物

母细胞瘤转移机制

Pre-mRNA processing factor 19 (Prp19) was previously reported to be involved in tumor progression. However, Prp19 expression and its functions remain elusive in neuroblastoma. Here, we aim to identify

NIAID Data Ecosystem30

Hijacking a neurodevelopmental epigenomic program in metastatic dissemination of medulloblastoma [Cut & Run]

母细胞瘤转移机制

表观遗传调控

How dysregulation of neurodevelopment relates to medulloblastoma (MB), the most common pediatric brain tumor, remains elusive. Here, we uncovered a neurodevelopmental epigenomic program being hijacked

NIAID Data Ecosystem80

LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene

母细胞瘤转移机制

组蛋白去甲基化

Neuroblastoma (NB) with MYCN amplification is a highly metastatic tumor in children, and unraveling the key players involved in MYCN-induced invasion may identify new targets for therapy. Epithelial-m

NIAID Data Ecosystem30

Clonal Selection Drives Genetic Divergence of Metastatic Medulloblastoma [Illumina Infinium HumanMethylation27 Beadchip v1.2]

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