Ventilation-induced changes in pulmonary microarchitecture and gene-expression profiles in SP-B deficient mice

Supplemental table 1: Bulk RNA-sequencing comparing ON-4DI and OFF-4DI Supplemental video 1: Microcomputed tomography of the right lung after 4 hours of low volume ZEEP ventilation before a deep inflation of a mouse assigned to ON-DI4 subgroup. Voxelsize: 6 µm. Supplemental video 2: Microcomputed tomography of the right lung after 4 hours of low volume ZEEP ventilation before a deep inflation of a mouse assigned to ON-DI4 subgroup. Voxelsize: 5.88 µm. Supplemental video 3: Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) of the cell-cell contacts between alveolar epithelial type 1 and type 2 cells of a mouse randomized to group ON-4DI. Based on this dataset, the model in Figure 8D was segmented. Supplemental video 4A: Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) of the cell-cell contacts between alveolar epithelial type 1 and type 2 cells of a mouse randomized to group OFF-4DI. Supplemental video 4B: Cropped dataset from 4A, focusing on the disorganized tight junction between alveolar epithelial type 1 and type 2 cells. Based on this dataset, the model in Figure 8B was segmented.