Predicted age-profiles of mf-prevalence from model fits to observed baseline and longitudinal post-intervention infection data.

Model outputs and observed data are shown for two of the PNG study villages exposed to high LF transmission intensity, and for both drug regimens used: Peneng (DEC+IVR) and Yauatong (DEC alone). Individual 500 best-fit model simulations are shown in grey while the thick blue line represents the median value of these curves. The observed data points (crosses) with 95% binomial credible intervals are shown at the mid-points of each 10-yearly age-group. The results for the remaining three study villages are exactly similar (Figure S1 in Supporting Information).