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Myeloid-derived Itaconate Suppresses Cytotoxic CD8+ 1 T Cells and Promotes Tumor Growth

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE211255
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To investigate the effect of itaconate on CD4+ T cells, we treated the purified splenic CD4+ T cells with NaCl or itaconate, and then performed the gene expression profilling analysis using data from RNA-seq of 2 different treatment cells. Comparative gene expression profiling analysis of RNA-seq data for NaCl (Ctrl) or itaconate (ITA) treatment of mouse splenic CD4+ T cells
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2022-11-15
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