Copper-Catalyzed Annulative Coupling of S,S-Disubstituted Enones with Diazo Compounds to Access Highly Functionalized Thiophene Derivatives
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https://figshare.com/articles/dataset/Copper-Catalyzed_Annulative_Coupling_of_S_S-Disubstituted_Enones_with_Diazo_Compounds_to_Access_Highly_Functionalized_Thiophene_Derivatives/11499729
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资源简介：
An efficient protocol toward fully
substituted thiophenes and thieno[2,3-b]thiophenes
has been developed through CuCl2-catalyzed annulative coupling
of S,S-disubstituted enones with diazo
compounds under mild conditions. Tetrasubstituted thiophenes and thieno[2,3-b]thiophenes were efficiently accessed by variation of the
feed ratio of the reactants in good to excellent yields, respectively.
The synthetic methodology has demonstrated the potential for the construction
of diverse thiophene derivatives.
创建时间：
2019-12-20
