RNA-sequence data of liver sinusoidal endothelial cells in wild type and endothelial RBPj-conditional knock out (RBPjcKO) mice

The Notch pathway plays a critical role in regulating the proliferation and differentiation of endothelial cells during liver homeostasis, so we used EC-specific RBPj conditional knock out mice, and compared the gene expression profiles of LSECs isolated from wild type versus RBPjcKO mice. Overall design: Liver sinusoidal endothelial cells mRNA profiles of 7- to 8-weeks-old wild type (WT) and RBPjcKO mice were generated by RNA sequencing, in triplicate, using Illumina HiSeq 3000.