five

Evaluation of the p53 isoform Δ133p53β aggregation capacity

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https://www.omicsdi.org/dataset/pride/PXD022998
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资源简介:
p53 isoforms and particularly Δ133p53β play a critical role in cancer progression. We demonstrate that WT Δ133p53β activity is regulated through an aggregation-dependent mechanism. Creation of WT Δ133p53β aggregates depends on associations with specific interacting partners and was observed both in cancer cell lines and in human tumour biopsies.
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2021-06-04
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