Median levels of analytes (pg/ml) and ranges (in parenthesis), and accuracies in discriminating between active TB disease and LTBI in all QFT-IT positive participants.

Participants were not stratified according to HIV status prior to analysis. Only analytes that showed significant differences or trends according to the Mann Whitney U test are shown. Analytes that discriminated between active TB disease and LTBI with AUC ≥0.70 after ROC analysis are highlighted in bold. Cut-off values were determined based on the highest likelihood ratio. Sensitivity and specificity are expressed as a percentage. AUC = Area under the ROC curve, 95% CI = 95% confidence interval.