Cyclocondensation of 5-Phenyl-2-amino-1,3,4-thiadiazole (2) with 1-Adamantyl bromomethylketone (1) under various reaction conditions to form title compounds.
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aReaction temperature = 80°CbReaction temperature = 95°CcReaction temperature = 120°CdReaction temperature = 60°C.It can be seen that using nano-MgO as a base and employing ionic liquids instead of traditional organic solvents considerably increase yields above 90%.
创建时间：
2015-12-03
