A NAFLD Model Created By Endoplasmic Reticulum Stress Response-Associated Steatosis in Human Induced Pluripotent Stem Cell-Derived Hepatocytes
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资源简介：
Our study reports a phenotypic approach to model hepatic steatosis in induced pluripotent stem cell-derived hepatocytes Overall design: hiPSCs, differentiated into functional hepatocytes that exhibited classic hepatocyte-associated bio-functions, were subjected to lipid overload and challenged with acute induced-ER stress developed a steatotic phenotype used to model hepatic steatosis in vitro. The quantification of lipid induction was performed by fluorescent high-content imaging.
创建时间：
2021-01-05
