Gene set enrichment analysis of genes whose expression was associated with genetically proxied serum ACE inhibition (at P value −3).

Caption: Category = one of 9 “major collections” included in the MSigDB, GeneSet = name of gene set as provided by MSigDB, N_genes = number of genes in gene set, N_overlap = number of overlapping genes from wGRS analysis in gene set, p = p-value (unadjusted for multiple testing), adjP = p-value (adjusted for multiple testing), genes = genes from wGRS analysis that overlap with gene set, link = link to further information on gene set. ACE, angiotensin-converting enzyme; MSigDB, Molecular Signatures Database; wGRS, weighted genetic risk score. (XLSX)