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Iminolactones from Schizophyllum commune

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Figshare2016-02-13 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Iminolactones_from_i_Schizophyllum_commune_i_/2164678
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Schizines A (1) and B (2), the first naturally occurring iminolactones (3,6-dihydro-2H-1,4-oxazin-2-one derivatives) to be reported, have been isolated from the fruiting bodies of Schizophyllym commune. In principle the 2-oxazinone moiety might have been formed by a reaction between the amino acid phenylalanine or tryptophan and an 2α-hydroxy-1-ketomarasmone. The alkaloids are unusual in that the carboxyl group of the amino acid precursor is preserved during the biosynthesis. The compounds showed some inhibition of the growth of cancer cells.
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2016-02-13
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