Targeted Cortical Reorganization using Optogenetics in Non-human primates: Electrocorticography in Sensorimotor Cortex during Optogenetic Stimulation

The data consists of electrocorticography (ECoG) recordings over primary somatosensory and primary motor cortices in two rhesus macaques that expressed C1V1 optogenetic channels in pyramidal neurons. The experimental setup, including the optogenetic expression and simultaneous ECoG and laser stimulation, are detailed in (Yazdan-Shahmorad et al., 2016). Â This dataset was collected during a series of ~1.5hr long experiments in which laser pulse trains were used to repeatedly stimulate one or two cortical sites. Each experiment was organized into blocks: Recording Blocks: Passive recordings were conducted during spontaneous activity (30 s or 5 min) Testing Blocks: 100 laser pulses were delivered with each laser, each in separate, interleaved blocks (10 pulses, 5ms @ 5 or 7Hz). ECoG signals were recorded simultaneously. Conditioning Blocks: Laser pulses were delivered through each laser (5ms pulses @ 5 or 7Hz) for 10min. The second laser had a fixed delay rel...本数据集包含两只在锥体神经元中表达C1V1光遗传通道的恒河猴的初级躯体感觉皮层与初级运动皮层的皮层脑电（electrocorticography, ECoG）记录。该实验装置（涵盖光遗传表达操作、同步皮层脑电记录与激光刺激流程）的详细信息已在Yazdan-Shahmorad等人2016年的研究中详述。 本数据集采集自一系列时长约1.5小时的实验，实验中通过激光脉冲串反复刺激单个或两个皮层位点。每项实验均分为多个实验区块： 记录区块：于动物自发活动状态下开展被动记录，单段记录时长为30秒或5分钟 测试区块：针对每台激光器分别递送100次激光脉冲，分设独立且交错的实验区块（单次刺激含10个脉冲，脉宽5ms，刺激频率为5Hz或7Hz），实验过程中同步记录皮层脑电信号 调控区块：通过每台激光器递送激光脉冲（脉宽5ms，刺激频率为5Hz或7Hz），持续时长10分钟。第二台激光器存在固定延迟……