HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE COMPLEXED WITH A NOVEL NON-SUBSTRATE INHIBITOR, 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE

Protein Data Bank Japan2023-08-16 更新2026-03-21 收录

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HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE COMPLEXED WITH A NOVEL NON-SUBSTRATE INHIBITOR, 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE Descriptor: 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE, PROTEIN (THYMIDINE KINASE), SULFATE ION Authors: Bennett, M.S, Wien, F, Champness, J.N, Batuwangala, T, Rutherford, T, Summers, W.C, Sun, H, Wright, G, Sanderson, M.R. Deposit date: 1999-05-12 Release date: 1999-07-09 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir. FEBS Lett., 443, 1999

单纯疱疹病毒I型胸苷激酶与新型非底物抑制剂9-(4-羟丁基)-N2-苯基鸟嘌呤复合物描述项：9-(4-羟丁基)-N2-苯基鸟嘌呤、蛋白质（胸苷激酶，Thymidine Kinase）、硫酸根离子作者：Bennett, M.S.、Wien, F.、Champness, J.N.、Batuwangala, T.、Rutherford, T.、Summers, W.C.、Sun, H.、Wright, G.、Sanderson, M.R. 存入日期：1999-05-12 发布日期：1999-07-09 最后修改日期：2023-08-16 实验方法：X射线衍射（分辨率1.9 Å）引用文献：新型非底物抑制剂与单纯疱疹病毒1型胸苷激酶复合物的1.9 Å分辨率结构：与阿昔洛韦结合模式的X射线晶体学对比。《FEBS快报》，443卷，1999年

创建时间：

1999-05-12