Lipid levels and CVD outcome in RA patients across different APOE genotype groups.

LDL: low density lipoproteins, HDL; High density lipoproteins, IMT; intima-media thickness (mm), CVD event; cardiovascular disease event (see Methods sections). All lipids are measured in mmol/L. Lipid levels and IMT were compared using ANCOVA, and unadjusted mean values with standard deviation (sd) are given in column 2, 3 and 4. CVD outcomes, which included previous CVD events or carotid plaques present on ultrasound (or both) were compared using Chi-square test; and the number of individuals affected with percentages [%] are given in column 2, 3 and 4. Multivariate analyses were adjusted for age, sex and current statin use. Not all patients had data on all variables and patients with genotype ε2/ε4 (n = 4) were omitted from the analyses.*p-values were corrected for multiple testing using Dunnets-Hsu adjustment.$Exact test.