首页/数据集/Plasmacytoid Dendritic Cells are Not Major Producers of Type 1 Interferon in Cutaneous Lupus: An In Depth Immunoprofile of Subacute and Discoid Lupus

Plasmacytoid Dendritic Cells are Not Major Producers of Type 1 Interferon in Cutaneous Lupus: An In Depth Immunoprofile of Subacute and Discoid Lupus

NIAID Data Ecosystem2026-05-01 收录

皮肤红斑狼疮免疫学

浆细胞样树突状细胞功能

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资源简介：

Plasmacytoid Dendritic Cells are Not Major Producers of Type 1 Interferon in Cutaneous Lupus: An In Depth Immunoprofile of Subacute and Discoid Lupus Journal of Investigative Dermatology

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创建时间：

2023-11-21

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浆细胞样树突状细胞功能

Pharmacological inhibition of epigenetic enzymes can have therapeutic benefit against hematological malignancies. Apart from affecting tumor cell growth and proliferation, these epigenetic agents may

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Supporting data for "The roles of plasmacytoid dendritic cells on the tumor immune microenvironment and surgical stress-induced tumor recurrence in hepatocellular carcinoma"

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Plasmacytoid dendritic cells (pDCs), a unique subset of dendritic cells, play immunosuppressive roles in the tumor microenvironment. However, the molecular mechanisms underlying pDC dysfunction in tum

DataCite Commons2021-08-25 更新50

Data_Sheet_4_An Inflammatory Loop Between Spleen-Derived Myeloid Cells and CD4+ T Cells Leads to Accumulation of Long-Lived Plasma Cells That Exacerbates Lupus Autoimmunity.PDF

皮肤红斑狼疮免疫学

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Splenic long-lived plasma cells are abnormally numerous and deleterious in systemic autoimmune diseases, yet how they accumulate remains poorly understood. We demonstrate here that a pathological role

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Table_1_Zika Virus Inhibits IFN-α Response by Human Plasmacytoid Dendritic Cells and Induces NS1-Dependent Triggering of CD303 (BDCA-2) Signaling.docx

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Zika virus (ZIKV) dramatically emerged in French Polynesia and subsequently in the Americas where it has been associated with severe neurological complications in adults and newborns, respectively. Al

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IFNβ expression is restricted to a subpopulation of splenic pDCs exhibiting a specific immune modulatory transcriptome signature. Mus musculus

浆细胞样树突状细胞功能

I型干扰素

Type I IFNs are critical in initiating protective antiviral immune responses and plasmacytoid DCs (pDCs) represent a major source of these cytokines. Here we show that only few pDCs are capable to pro

NIAID Data Ecosystem40

Plasmacytoid Dendritic Cells are Not Major Producers of Type 1 Interferon in Cutaneous Lupus: An In Depth Immunoprofile of Subacute and Discoid Lupus

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