Structure of the KcsA-W67F mutant with the activation gate in the closed conformation

Protein Data Bank Japan2024-10-23 更新2026-04-19 收录

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Structure of the KcsA-W67F mutant with the activation gate in the closed conformation Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Fragment, KcsA potassium channel, ... Authors: Cuello, L.G, Labro, A.J. Deposit date: 2021-11-07 Release date: 2022-10-12 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.21 Å) Cite: The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels. Sci Adv, 8, 2022

带有关闭构象激活门的KcsA-W67F突变体结构描述项：(1S)-2-羟基-1-[(壬酰氧基)甲基]十四酸乙酯、抗体片段、KcsA钾离子通道等作者：Cuello, L.G.、Labro, A.J. 提交日期：2021-11-07 发布日期：2022-10-12 最后修改日期：2024-10-23 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率3.21埃（Å）引用文献：非导电型W434F突变体经膜去极化后会呈现一种不同于野生型Shaker-IR钾离子通道的类失活状态。《科学进展》（Sci Adv），8卷，2022年

创建时间：

2021-11-07