Supplemental Material for Siebert et al., 2022

This data set represents the results of RNA-seq transcriptome analysis for the submitted revised manuscript entitled: Genetic Analysis of Human RNA Binding Motif Protein 48 (RBM48) Reveals an Essential Role in U12-Type Intron Splicing <br> Dataset S1. Read counts and statistics for individual introns and exon-exon junctions detected in RNA-seq experiments. Intron coordinates are given for the Homo_sapiens.GRCh38.87 reference genome annotation. Intron reads and exon-exon junction reads are summed by Vector Control (VC) and Knockout (KO) K-562 sublines for all biological replicates. Introns were filtered for overlap with the MIDB dataset (see RNA-seq Methods in main article). Prior to analysis, introns were filtered for a minimum sum of 10 total exon-exon junction and intronic read counts with an intronic density (Di) &gt; 0 in both VC or KO populations. Dataset S2. Read counts for individual introns and exon-exon junctions for each biological<br> replicate from Vector Control (VC) and Knockout (KO) K-562 sublines detected in RNA-seq experiments.