five

Fig. 4a

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Raji cells and Raji cells expressing the MICA*001 allele were incubated for 1, 4 or 16 hours (overnight) with MICAB1 or isotype control mAbs coupled to a pH-sensitive cyanine dye (Cyp5). FACS profiles showing dye fluorescence upon anti-MICA mAb internalization are shown. Representative data from two independent experiments are shown 19E9 = MICAB1 antibody 15C11 = Control Antibody
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