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THP1 derived macrophage and foam cell gene expression in presence and absence of T0901317 and RNAi analyses of LXRa/b

ChEBI2013-02-15 更新2026-07-21 收录

泡沫细胞形成

LXR信号通路调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-1106 数据链接链接失效反馈

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资源简介：

THP1 derived macrophage and foam cell gene expression in presence and absence of T0901317 and RNAi analyses of LXRa/b

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2013-02-15

动脉粥样硬化

泡沫细胞形成

Introduction: Atherosclerosis is the main cause of many cardiovascular diseases and contributes to morbidity and mortality worldwide. The formation of macrophage-derived foam cells plays a critical ro

NIAID Data Ecosystem50

Profile of IL-6 and TNF in Foam Cell Formation: An Improved Method Using Fluorescein Isothiocyanate (FITC) Probe

动脉粥样硬化

泡沫细胞形成

Abstract Background The formation of foam cells occurs due to the increase in low-density plasma lipoprotein (LDL) and dysregulation of inflammation, which is important for the development of athero

NIAID Data Ecosystem50

A study of the effect of OxLDL on C/EBP beta binding in human macrophages using chromatin immunoprecipitation for C/EBP beta with high throughput sequencing (ChIP-seq)

转录因子结合位点分析

泡沫细胞形成

We report the C/EBP beta transcription factor binding landscape in human macrophages and oxLDL-induced foam cells Overall design: ChIP-seq for C/EBP beta binding was performed in human macrophages and

NIAID Data Ecosystem30

11β-Hydroxysteroid Dehydrogenase Type 1 Gene Knockout Attenuates Atherosclerosis and In Vivo Foam Cell Formation in Hyperlipidemic apoE −/− Mice

动脉粥样硬化斑块发展

泡沫细胞形成

BackgroundChronic glucocorticoid excess has been linked to increased atherosclerosis and general cardiovascular risk in humans. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) increases a

NIAID Data Ecosystem50

Gene expression in primary human macrophages and foam cells. Homo sapiens

动脉粥样硬化机制

泡沫细胞形成

The aim of the experiment was to determine the effects of 48 hours of treatment with oxidized low density lipoprotein (oxLDL) on gene expression in primary human monocyte-derived macrophages. Overall

NIAID Data Ecosystem40

THP1 derived macrophage and foam cell gene expression in presence and absence of T0901317 and RNAi analyses of LXRa/b

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