Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10
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Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10 Descriptor: 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... Authors: Wedekind, J.E, Spitale, R.C, Krucinska, J. Deposit date: 2009-06-29 Release date: 2009-11-03 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
携带2',5'-连接底物且A10位为N1-脱氮腺苷(N1-deazaadenosine)的发夹核酶(hairpin ribozyme)晶体结构 描述符:5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3'、5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'、六氨合钴(III)(COBALT HEXAMMINE(III)),…… 作者:Wedekind, J.E.、Spitale, R.C.、Krucinska, J. 沉积日期:2009年6月29日 发布日期:2009年11月3日 最后更新日期:2023年9月6日 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.8埃(2.8 Å) 引用文献:《A9与A10位单亚氨基原子替换揭示发夹核酶催化核心折叠与功能的差异效应》,《生物化学(Biochemistry)》,第48卷,2009年



