Altered cartilage gene expression in Aga2 OI mouse negatively impacts linear growth through Sox9 and FGF signaling
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE231795
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资源简介:
Osteogenesis Imperfecta is characterized by short stature however the cellular mechanisms behind this phenotype are unclear. We isolated tibial and femoral cartilage growth plate chondrocytes from postnatal day 5 wild type and Aga2 (a model of OI) mice and analyzed differential expression patterns using single cell RNA-seq Growth plate chondrocytes from Wild-type and Aga2 mice were isolated from femoral and tibial cartilage tissue at postnatal day 5 and analyzed using scRNAseq.
创建时间:
2023-12-01



