Clec4e
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1551121
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资源简介：
Enables glycolipid binding activity and pattern recognition receptor activity. Involved in antifungal innate immune response and positive regulation of cytokine production. Acts upstream of or within Fc-gamma receptor signaling pathway; T cell differentiation involved in immune response; and defense response to bacterium. Is active in phagocytic vesicle membrane and plasma membrane. Orthologous to human CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Nov 2024]
激活糖脂结合活性和模式识别受体活性。参与抗真菌固有免疫反应及细胞因子生产的正性调控。位于Fc-γ受体信号通路的上游或其中；涉及免疫反应中的T细胞分化；以及对抗细菌的防御反应。在吞噬小体膜和质膜上具有活性。与人源CLEC4E（C型凝集素结构域家族4成员E）同源。[由基因组资源联盟提供，2024年11月]
提供机构：
Rat Genome Database
