首页/数据集/RNA processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA.

RNA processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA.

Alliance of Genome Resources2026-08-01 收录

DNA损伤修复

ATR激酶激活机制

数据链接：

https://www.yeastgenome.org/dataset/GSE63444 数据链接链接失效反馈

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资源简介：

Eukaryotic cells respond to DNA double-strand breaks (DSBs) by activating a checkpoint that depends on the protein kinases Tel1/ATM and Mec1/ATR

应用场景：

DNA损伤修复

断裂诱导复制(BIR)

Source data for ‘53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)’

Figshare2024-10-06 更新20

Dataset for: Interaction of replication protein A with two acidic peptides from human Bloom syndrome protein

蛋白质相互作用

DNA损伤修复

Bloom syndrome protein (BLM) is one of five human RecQ helicases which maintain genomic stability. Interaction of BLM with replication protein A (RPA) stimulates the DNA unwinding ability of BLM. The

WILEY2018-02-15 更新10

Dataset for: A newly identified photolyase from Arthrospira platensis possesses a unique MTHF binding model

DNA损伤修复

光解酶机制

Cyclobutane pyrimidine dimers (CPD), as a common DNA damage caused by UV radiation, often lead to disastrous diseases. Here, we identified a photolyase from Arthrospira platensis (designated as Ap-phr

Figshare2019-11-01 更新00

Active DNA demethylation promotes cell fate specification and the DNA damage response [RNA-Seq]

表观遗传调控

DNA损伤修复

Neurons harbor high levels of endogenous single strand DNA breaks (SSBs) that are targeted to neuronal enhancers and correlate with marks of DNA demethylation. To determine the source of SSBs at neuro

NIAID Data Ecosystem20

The histone chaperone CAF-1 prevents homologous recombination-mediated instability of the budding yeast ribosomal DNA during replication-coupled DNA double-strand break repair

DNA损伤修复

DNA稳定性

Raw data for the paper, titled "The histone chaperone CAF-1 prevents homologous recombination-mediated instability of the budding yeast ribosomal DNA during replication-coupled DNA double-strand break

DataCite Commons2025-09-10 更新10

RNA processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA.

资源简介：

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