RPFdb

RPFdb is a database for genome wide information of translated mRNA generated from ribosome profiling.RPFdb v3.0 is a majorly upgraded repository for ribosome profiling (Ribo-seq) data, now integrating 5,018 Ribo-seq and 2,343 matched RNA-seq datasets across 34 species. It features translation efficiency metrics, pausing scores for ribosome-enriched motifs, sensitive ORF detection via RibORF v2.0, and a redesigned user-friendly portal for streamlined translatomics analysis.

搜集汇总

背景与挑战

背景概述

RPFdb是一个专注于核糖体分析（Ribo-seq）数据的公共数据库，最新版本v3包含5,018个Ribo-seq样本和2,343个匹配RNA-seq样本，覆盖34个物种。它提供多层级数据组织（研究、样本、基因和翻译效率），并支持基因组浏览器查询和可视化，以及开放阅读框（ORF）和暂停评分等注释信息，适用于翻译调控研究。