H‑Bond-Directing Organocatalyst for Enantioselective [4 + 2] Cycloadditions via Dienamine Catalysis
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/H_Bond_Directing_Organocatalyst_for_Enantioselective_4_2_Cycloadditions_via_Dienamine_Catalysis/2071546
下载链接
链接失效反馈官方服务：
资源简介：
An efficient, highly regio- and stereoselective
[4 + 2] cycloaddition
reaction to generate tetrahydropyranopyrazole frameworks has been
developed. To this end, a dienamine-based catalytic strategy that
relies on the H-bond-directing effect of the hydroxy group of a dinaphthylprolinol-type
aminocatalyst has been used. This enables the synthesis of multifunctionalized
heterocyclic derivatives with three contiguous stereocenters in good
yields and excellent enantioselectivities.
创建时间：
2016-02-04
