Single-cell dissection of the immune response after a myocardial infarction
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001007021
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The immune response plays a pivotal role in initiating cardiac repair and remodeling in both the acute and chronic phase after ST-Elevated myocardial infarction (STEMI). To dissect the longitudinal character of the immune response in STEMI patients over time, we performed single-cell RNA-sequencing (scRNA-seq) on a total of 95,995 peripheral blood mononuclear cells (PBMCs) collected from 38 STEMI patients at hospital admission, 24 hours (acute phase) and 6-8 weeks (chronic phase) after STEMI. Additionally, comparison to healthy controls was performed using previously generated scRNA-seq data on 33,878 PBMCs from 38 age- and sex-matched healthy controls from the Dutch population cohort Lifelines DEEP.EGA study EGAS00001007021
创建时间:
2023-10-16



