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KRAB/KAP1-microRNA cascade regulates erythropoiesis through the stage-specific control of mitophagy [array]

ChEBI2013-04-03 更新2026-07-21 收录

红细胞生成调控

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44063 数据链接链接失效反馈

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KRAB/KAP1-microRNA cascade regulates erythropoiesis through the stage-specific control of mitophagy [array]

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创建时间：

2013-04-03

帕金森病

线粒体自噬

Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how

DataCite Commons2020-08-28 更新120

Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples

线粒体自噬

ELISA检测

Mitochondrial dysfunction is an early, imminent event in neurodegenerative disorders including Parkinson disease (PD) and Alzheimer disease (AD). The enzymatic pair PINK1 and PRKN/Parkin recognize and

DataCite Commons2021-10-13 更新80

ATAC-seq reveals GATA-1- and heme-dependent chromatin targeting in erythroid cells.

红细胞生成调控

染色质可及性分析

CRISPR/Cas9-mediated ablation of two Alas2 intronic cis-elements in G1E-ER-GATA1 cells strongly reduced GATA-1-induced Alas2 transcription, heme biosynthesis, and GATA-1 regulation of other vital cons

NIAID Data Ecosystem50

PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window

脑缺血治疗

线粒体自噬

Prompt reperfusion after cerebral ischemia is critical for neuronal survival. Any strategies that extend the limited reperfusion window will be of great importance. Acidic postconditioning (APC) is a

Mendeley Data2024-06-25 更新110

Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP

蛋白激酶结构

线粒体自噬

Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PINK1, ...

Protein Data Bank Japan2024-10-23 更新50

KRAB/KAP1-microRNA cascade regulates erythropoiesis through the stage-specific control of mitophagy [array]

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