Losses of the power for α = 0.05&.

&: The values are differences of power between the situation with none of the causal variants (i.e., 0%) being negative and the situation with 30% or 50% causal variants being negative.#: It means that 30% or 50% causal variants are negatively related to phenotype with effects −0.3|log10MAF| and the rest 70% or 50% are positively related to phenotype with effects 0.3|log10MAF|.$: The average is calculated across sample sizes.