MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis

We determined transcriptomic profile in the liver and epididymal white adipose tissue (eWAT) from wild-type (WT) and MAD2 binding deficient IR 4A mice after 6 hour fasting using RNA sequencing. Overall design: RNA-seq of livers and epididymal white adipose tissues (eWAT) from 2 month old male mice (WT, liver, n=5; WT, eWAT, n=5; IR 4A, liver, n=5; IR 4A, eWAT, n=5)