Dataset for the paper entitled "A genetic map of the response to DNA damage in human cells" by Olivieri M et al. Cell 2020

We used pooled CRISPR/Cas9 screens in the human RPE1-hTERT p53-/- cell line against 27 genotoxic agents. The Dataset herein make the primary data available. The files are:

* Additional genes of interest (discussion and data relating to TMEM2, ESD, USP37, PHF12, BTAF1 and DRAP1)
* Supplementary Raw Data: Data used to make all the graphs in the manuscript
* Folder "CRISPR screen readcount files". Readcounts for the screens undertaken as part of this study.
* Folder "Raw images for immunoblots": uncropped images for all the blots in the manuscript
* Folder: "Additional QC analyses of CRISPR screens": Additional analyses that measure the quality of the screens using Presion-Recall curves of essential genes and an estimate of genes that scored as hits due to batch effects.
* Folder "Data_Analysis_Code" R markdown file along with data files
* File: "Additional Genes of Interests" contains a short discussion of genes we found noteworthy after analysis of our screen data.

Version 2 note: this version differs from Version 1 by a single file (FDRPos_31screens.csv) which has a tab error fixed.