Identification of SRSF6 splicing regulatory map and its impact on diabetes susceptibility genes regulation
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP260902
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资源简介:
The downregulation of diabetes susceptibility gene GLIS3 contributes to pancreatic beta cell demise, at least in part, through downregulation of the splicing factor SRSF6. Here, we used individual-nucleotide UV crosslinking and immunoprecipitation (iCLIP) to map the RNA binding landscape of SRSF6 in pancreatic beta cells. Overall design: Four independent iCLIP replicates for endogeneous SRSF6 from human pancreatic beta cells (EndoC-ÃH1 cell line)
创建时间:
2021-01-20



