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JIP1 knockout in PE and TSA treated NRVMS. Rattus norvegicus

NIAID Data Ecosystem2026-03-10 收录

心肌细胞转录组学

基因敲除与药物处理

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA398202 数据链接链接失效反馈

官方服务：

资源简介：

Jip1 was knocked out in neonatal rat ventricular myocytes in the presence of phenylephrine and trichostatin a Overall design: rnaseq of cardiomyocytes

应用场景：

创建时间：

2017-08-14

心肌细胞转录组学

基因敲除功能研究

To characterize transcriptome changes uopn Myocd KO, Mrtfa/b DKO and Mrtfa/b/Myocd TKO in maturing cardiomyocytes AAV-Cre or AAV-Myocd-sgRNAwere injected into P1 Rosa-Cas9GFP or Mrfta-/-; Mrtfb-F/F;

NIAID Data Ecosystem70

RNA-Seq of Ctrl, Myocd KO, Mrtfa/b DKO and TKO cardiomyocytes

心肌细胞转录组学

基因敲除模型

To characterize transcriptome changes uopn Myocd KO, Mrtfa/b DKO and Mrtfa/b/Myocd TKO in maturing cardiomyocytes Overall design: AAV-Cre or AAV-Myocd-sgRNAwere injected into P1 Rosa-Cas9GFP or Mrfta

NIAID Data Ecosystem40

RNA sequencing of NMCMs

心肌细胞转录组学

基因表达调控

RNA samples came from NMCMs infected with adenoviruses expressing GFP (Ad-ZsGreen or Ad-ZsGreen-mOGDHL) and subsequently treated with DOX (n=3).

NIAID Data Ecosystem30

Table_2_Transcriptomic Coupling of PKP2 With Inflammatory and Immune Pathways Endogenous to Adult Cardiac Myocytes.xlsx

心肌细胞转录组学

心脏炎症免疫机制

Plakophilin-2 (PKP2) is classically defined as a component of the desmosome. Besides its role in cell–cell adhesion, PKP2 can modulate transcription through intracellular signals initiated at the site

NIAID Data Ecosystem50

Gene expression profiling of hypertrophic and failing cardiomyocytes identifies new players in heart failure. Gene expression profiling of hypertrophic and failing cardiomyocytes identifies new players in heart failure

心力衰竭基因表达

心肌细胞转录组学

Aim - Pathological cardiac remodeling is characterized by cardiomyocyte hypertrophy and fibroblast activation, which can ultimately lead to heart failure (HF). Genome-wide expression analysis on heart

NIAID Data Ecosystem40

JIP1 knockout in PE and TSA treated NRVMS. Rattus norvegicus

资源简介：

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