DELIVERY， CONSTRUCTION AND OPTIMIZATION OF SYSTEMS， METHODS AND COMPOSITIONS FOR TARGETED ACTION AND MODELING OF DISEASES AND DISORDERS OF POSTMITOTIC CELLS
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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资源简介：
FIELD: biotechnology. SUBSTANCE: disclosed is a composition containing a CRISPR-Cas system for use in treating a postmitotic cell disorder， where Cas9 contains at least one nuclear localization sequence. What is also presented is using the composition containing polynucleotides expressing Cas9， containing at least one nuclear localization sequence， a guide sequence， a paired tracr-sequence and a tracr-sequence， to obtain a composition， containing CRISPR-Cas system for use in treating postmitotic cell disorders. EFFECT: this group of inventions provides targeted gene editing， in connection with which can be used in gene therapy. 30 cl， 76 dwg， 17 tbl， 38 ex
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
