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Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP505183
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This bulk RNAseq dataset is part of a dataset described in the manuscript titled "Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation". This dataset includes NPC derived neurons using a wild type iPSC line, and was used to validate a MS-117 maturation score which attempt to establish a socre system to assess neuronal maturation with iPSCs derived neurons. Overall design: Three technical replicates were included, and cells were profiled at the NPC stage, as well as cultures undergo neuronal differentiation and maturation at 4 weeks, weeks and 12 weeks upon the induction of terminal differentiation.
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2024-09-14
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