Synthesis of Functionalized 6‑Hydroxy-2-oxindole Derivatives by Phenoxide Cyclization
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https://figshare.com/articles/dataset/Synthesis_of_Functionalized_6_Hydroxy-2-oxindole_Derivatives_by_Phenoxide_Cyclization/4251863
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资源简介:
An
apparent intramolecular cross-dehydrogenative coupling of N-(3-hydroxy)monoanilide of maleic esters comprising
base promoted phenoxide cyclization and subsequent base-mediated aerobic
oxidation was developed to synthesize a variety of 2-(6-hydroxy-2-oxoindolin-3-ylidene)acetate
derivatives. The isolation of intermediate cyclized products during
the large scale reactions and their ready dehydrogenation with 1 equiv
of base support this proposed two-step path.
创建时间:
2016-11-23



