Codon based Z tests of selection.

The test statistic dN-dS is shown above the diagonal. dN and dS are the values of non-synonymous and synonymous substitutions per site, respectively. The Nei-Gojobori method was used to calculate synonymous and nonsynonymous substitutions. The probability of rejecting the null hypothesis of strict-neutrality (dN = dS) is shown below the diagonal). Values of P less than 0.05 are highlighted in bold. Values were not significant after Bonferroni correction. The variance of the difference was computed using the bootstrap method (500 replicates). Numbers listed for columns represent the same KoRV sequences numbered in the rows. The first two KoRV sequences are from GenBank; the other KoRVs are consensus sequences from the current study.