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Pvt1 silencing in C2C12 cell cultures

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NIAID Data Ecosystem2026-03-10 收录
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In order to understand the role of lncRNA Pvt1 in skeletal muscle physiopathology we silenced this transcript in-vitro, using C2C12 cell cultures, and in-vivo, in leg muscles of CD1 wild-type and denervated mice. In vitro Pvt1 silencing experiments were performed on proliferating C2C12 myoblasts using antisense LNA GapmeRs specific for Pvt1. Silencing efficiency was assessed by qRT-PCR.

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2019-02-04
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